Author

Danielle M. Simons

McGill UniversityORCID 0009-0003-0154-0279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew N. BayneiD· 1 shared Edward A. FoniD· 1 shared Gergely L. LukácsiD· 1 shared Jean‐François TrempeiD· 1 shared Karl Grenier· 1 shared Naoto SoyaiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Andrew N. BayneORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedOct 27, 2025

Substrate recognition by the human mitochondrial processing peptidase and its processing of PINK1

Andrew N. Bayne, Danielle M. Simons, Naoto Soya…·Jean‐François Trempe

This study investigates how the human mitochondrial processing peptidase (MPP) recognizes and processes the N-terminal targeting sequence of PINK1, revealing its binding mechanism and functional implications.

6 citations

humanproteomics

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