Author

Alexander C. Wieland

University of SalzburgORCID 0009-0003-0311-3641Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Carina Horak· 1 shared Elfriede DalliD· 1 shared Hans BrandstetteriD· 1 shared Peter BrizaiD· 1 shared Rupert KlaushoferiD· 1 shared

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2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Carina Horak

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1 paper

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Molecular BiologyJournal of Molecular BiologyPeer-reviewedApr 5, 2025

Conformational and Functional Regulation of SET by Legumain Cleavage

Carina Horak, Alexander C. Wieland, Rupert Klaushofer…·Elfriede Dall

This study shows legumain cleaves SET at two sites, forming a stable complex and impairing its interaction with histone 1, while also abolishing SET's positive modulation of PP2A activity.

DOI 10.1016/j.jmb.2025.169119

experimental assay

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