Louis L’Hôte

PIGSTI detects species identity, pathogens, and microbes in ancient animal genomic data, identifying 15 zoonotic pathogens including Rickettsia felis and Leptospira borgpetersenii.

The paper reconstructs 3,500 years of sheeppox virus evolution using ancient genomes from archaeological and medieval parchment sources, showing divergence events and gene inactivation.

The paper analyzes ancient DNA from a 7,000-year-old goat leather specimen, revealing its domestic goat origin and genetic connections to modern Iberian breeds, while also identifying human and canid DNA fragments.

The paper identifies sheeppox virus in 17th-19th century French sheep remains using paleogenetics and interdisciplinary methods.