Synthetic BiologybioRxivPreprint
Quantitative profiling of millions of nucleotides reveals sequence-encoded interactions that govern plasmid propagation
Tom Copeman, John H.C. Fong, Joshua R Mayne…·Francesca Ceroni
The paper develops a sequencing-based framework and a neural network model to predict plasmid propagation from sequence, revealing sequence-encoded interactions that influence plasmid stability and host compatibility.
DOI 10.64898/2025.12.15.694402