Alan S.L. Wong

This paper introduces SpAD, a high-throughput label-free imaging platform for live-cell drug and genetic screens, enabling rapid, unbiased profiling of cellular responses.

This paper develops MTtrans, a multi-task learning model that identifies robust, generalizable cis-regulatory motifs in 5' UTRs by integrating diverse datasets, showing improved accuracy and cross-species transferability.

This study develops a high-throughput method to engineer 5' UTRs that enhance protein expression in non-viral gene therapies, identifying synthetic 5 UTRs that outperform existing plasmids.