Author

Rachel S Sousa

University of California, IrvineORCID 0009-0003-0896-6926Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Agata XellaiD· 1 shared Alexander MoshenskyiD· 1 shared Chandler GatenbeeiD· 1 shared Claire MuratiD· 1 shared Dawn LemanneiD· 1 shared Erin M. GeorgeiD· 1 shared Francesco MarangoniiD· 1 shared John S. LowengrubiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Agata XellaORCID

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2 papers

Recent·Most cited

ImmunologyCancer ResearchPeer-reviewedAug 20, 2026

Integrating Mathematical and Mouse Models Identifies T regulatory Cell Influx as a Key Determinant of Acquired Resistance to PD-1 Immunotherapy

Rachel S Sousa, Shannon N Geels, Claire Murat…·Francesco Marangoni

1 citation

mousemechanistic / dynamical model

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 10, 2025

Controlling treatment toxicity in ovarian cancer to prime the patient for tumor extinction therapy

Kit Gallagher, Rachel S Sousa, Chandler Gatenbee…·Maximilian A.R. Strobl

This paper develops computational frameworks to design personalized multi-strike therapies for ovarian cancer that reduce toxicity while enhancing tumor extinction.

DOI 10.1101/2025.07.10.664235

humanstatistical model

𝕏 PostBluesky