Author

Franklin Chien

Emory UniversityORCID 0009-0003-4206-8580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Jose E. Velazquez VegaiD· 2 shared Tobey J. MacDonaldiD· 2 shared Anshu MalhotraiD· 1 shared Chanel SchroffiD· 1 shared Dan Zhu· 1 shared Hongying ZhangiD· 1 shared Isabella GershoniD· 1 shared Jingbo LiuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Jose E. Velazquez VegaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyJCO Precision OncologyPeer-reviewedOct 1, 2026

Medulloblastoma Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity with High-Density Progenitor Cell Regions Correlating with High-Risk Disease

Franklin Chien, Marina E. Michaud, Mojtaba Bakhtiari…·Manoj K. Bhasin

This study uses spatial transcriptomics to analyze medulloblastoma tumor microenvironments, identifying high-risk features and spatial patterns linked to relapse.

6 citationstop 1%

humanspatial transcriptomics

𝕏 PostBluesky

Cancer BiologyNeuro-OncologyPeer-reviewedMar 6, 2026

ONC206 demonstrates potent anti-tumorigenic activity and is a potential novel therapeutic strategy for high-risk medulloblastoma

Theophilos Tzaridis, Jingbo Liu, Franklin Chien…·T. MacDonald

This study shows ONC206 effectively kills medulloblastoma cells and extends survival in mouse models, supporting its potential as a new treatment for high-risk medulloblastoma.

3 citationstop 1%

mousehuman

𝕏 PostBluesky