Z Chen

This study designs DNA condensates that control their interaction with cell membranes, showing that internalization depends on a balance between adhesion and fluidity, not just affinity.

ANCHOR improves variant calling and allele-specific expression analysis in single-cell long-read RNA-seq by integrating haplotype-aware methods and beta-binomial modeling.

This study identifies ZCWPW2 as a dual histone methylation reader that links H3K4me3 and H3K36me3 to meiotic DSB formation by interacting with key recombination proteins.