Chuanxin Zhang

ANCHOR improves variant calling and allele-specific expression analysis in single-cell long-read RNA-seq by integrating haplotype-aware methods and beta-binomial modeling.

The paper quantifies poly(A) tail length dynamics during the mammalian oocyte-to-embryo transition and shows their role in maternal gene expression across species.

This study identifies ZCWPW1 as an H3K4me3 reader required for DSB repair and synapsis in mouse testes, showing its dependency on PRDM9 activity.