Author

Smriti Vaidyanathan

Brown UniversityORCID 0009-0003-4707-5499Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Ashley Mae ConardiD· 2 shared Erica LarschaniD· 2 shared Mukulika RayiD· 2 shared Pranav Mahableshwarkar· 2 shared Aaron ZweigiD· 1 shared Alexander E. ConicellaiD· 1 shared Annie HuangiD· 1 shared Annie HuangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersGenomics

Ashley Mae ConardORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintNov 26, 2025

Robust Integration of Sparse Single-Cell Alternative Splicing and Gene Expression Data with SpliceVI

Smriti Vaidyanathan, Keren Isaev, Aaron Zweig, David A. Knowles

SpliceVI integrates sparse single-cell alternative splicing and gene expression data to better capture biological correlates and uncover splicing-based differences in mouse cells.

2 citations

mousescRNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 11, 2024

A dual DNA/RNA-binding factor regulates co-transcriptional splicing through target RNA interaction and modulates splicing factor dynamics

Mukulika Ray, Julia Zaborowsky, Pranav Mahableshwarkar…·Erica Larschan

The paper shows CLAMP, a DNA-binding factor, regulates sex-specific splicing by interacting with RNA and modulating RBP dynamics.

5 citations

humanDNA methylation

𝕏 PostBluesky

GenomicseLifePeer-reviewedJul 19, 2023

Sex-specific transcript diversity is regulated by a maternal pioneer factor in early Drosophila embryos

Mukulika Ray, Ashley Mae Conard, Jennifer A. Urban…·Erica Larschan

The paper identifies mechanisms by which the CLAMP TF regulates sex-specific splicing in Drosophila embryos through interactions with RBPs and gene regulation.

16 citations

Drosophilabulk RNA-seq

𝕏 PostBluesky