Mukulika Ray

This study maps sex-specific RNA-RNA and RNA-DNA interactions in Drosophila cells using RD-SPRITE, revealing CLAMP's role in spliceosome targeting and RNA regulation.

The paper shows how differential binding of two GA-binding transcription factors regulates chromatin looping to create an X-specific environment for dosage compensation.

BindCompare identifies combinatorial TF-RBP binding interactions by comparing their nucleic acid targets across organisms, generating hypotheses for gene regulatory networks.

The paper shows CLAMP, a DNA-binding factor, regulates sex-specific splicing by interacting with RNA and modulating RBP dynamics.

The paper identifies CLAMP as a transcription factor that regulates heat stress-induced repression of constitutive genes in Drosophila and presents a high-resolution 3D genomic dataset.

The paper identifies mechanisms by which the CLAMP TF regulates sex-specific splicing in Drosophila embryos through interactions with RBPs and gene regulation.

The paper shows that activated Ras/JNK signaling in Drosophila imaginal discs increases Dilp8 secretion, inhibits ecdysone synthesis, and causes early pupal death.

The paper shows that over-expression of Hsp83 in the absence of hsrω lncRNAs causes synthetic lethality and phenocopies l(2)gl mutants in Drosophila.