George Tsitsiridis

The paper benchmarks variant effect scores using UK Biobank data on ultra-rare variant carriers, showing coding and splicing scores better predict protein abundance and traits than transcriptional regulation models.

PROTRIDER detects protein expression outliers in proteomics data using conditional autoencoders, outperforming existing methods and revealing enrichments of pathogenic variants in outliers.

The paper maps aging in the lung using single cell transcriptomics and proteomics, identifying novel age-related changes in cell types and the extracellular matrix.

MetaMap provides an interactive webtool to explore metatranscriptomic data from human disease-related RNA-seq studies, enabling visualization and statistical analysis of microbial and viral reads.