SPT5 regulates Pol II pausing and elongation in different ways at early versus late embryonic stages
Alessandro Dulja, Marvin Mayer, Niklas L Engel, Arkadiy K. Golov, Mattia Forneris, Yacine Kherdjemil, Songjie Feng, Rebecca R. Viales, Eileen E. M. Furlong
This study shows SPT5 regulates Pol II pausing and elongation differently in early and late Drosophila embryogenesis, affecting gene expression dynamics.
bioRxiv · Sep 6, 2025 · PreprintGenomics