Author

Josephine Shepherd

Liverpool School of Tropical MedicineORCID 0009-0003-5869-9184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Amalia AnthousiiD· 2 shared Poppy PescodiD· 2 shared Tony NolaniD· 2 shared Ashley HalliD· 1 shared Carla Siniscalchi· 1 shared Fabrizio LombardoiD· 1 shared Giulia BevivinoiD· 1 shared Kurtis Blinkhorn· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Amalia AnthousiORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 11, 2026

Functional disruption of vgsc reveals haplosufficiency with implications for insecticide resistance and genetic control in Anopheles gambiae

Poppy Pescod, Ashley Hall, Sian Yates-Wakley…·Tony Nolan

This study generates CRISPR-edited Anopheles gambiae lines to investigate vgsc's role in insecticide resistance and genetic control, finding haplosufficiency and reduced susceptibility to pyrethroids.

DOI 10.64898/2026.09.09.750417

experimental assay

𝕏 PostBluesky

GeneticsThe CRISPR JournalPeer-reviewedSep 13, 2023

Measuring the impact of genetic heterogeneity and chromosomal inversions on the efficacy of CRISPR-Cas9 gene drives in different strains of Anopheles gambiae

Poppy Pescod, Giulia Bevivino, Amalia Anthousi…·Tony Nolan

This study evaluates how genetic variation and chromosomal inversions affect CRISPR-Cas9 gene drive homing in Anopheles gambiae strains, finding no significant reduction in homing despite target site heterogeneity.

13 citations

CRISPR screenexperimental assay

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