Author

Meaghan Donahue

Yale UniversityORCID 0009-0003-6025-8900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Oakleigh M. FolkesiD· 2 shared Paola N. Negrón-MorenoiD· 2 shared Yong-Hui JiangiD· 2 shared Angelica M. Minier-ToribioiD· 1 shared Ashley Pawelka· 1 shared Brendan LeeiD· 1 shared Carolina LeynesiD· 1 shared Hugh Stott TayloriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Oakleigh M. FolkesORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 1, 2026

Multi-omic profiling reveals impaired luteal resolution and CHK2-regulated inflammation in ovarian aging

Liubin Yang, Zhongwei Sun, Xinlong Luo…·Jason D. Heaney

This study identifies impaired luteal resolution and CHK2-regulated inflammation as features of ovarian aging in mice, showing that CHK2 inhibition can reverse these effects.

DOI 10.64898/2026.09.30.755521

mousebulk RNA-seq

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NeurosciencebioRxivPreprintJun 5, 2026

Social Novelty Recruits a Dysfunctional Nucleus Accumbens Ensemble That Drives Social Avoidance in a Shank3-/- Autism Model

Oakleigh M. Folkes, Meaghan Donahue, Rafael E. Perez…·Yong-Hui Jiang

This study identifies a dysfunctional nucleus accumbens ensemble in Shank3-/- mice that drives social avoidance by hyperresponding to social novelty.

DOI 10.64898/2026.06.04.730003

mouseexperimental assay

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NeuroscienceCommunications BiologyPeer-reviewedNov 14, 2025

Deficiency of Shank3 in the Nucleus Accumbens Reveals a Loss of Social-Specific Motivation

Oakleigh M. Folkes, Meaghan Donahue, Sung Eun Wang…·Yong‐hui Jiang

This study shows that reducing Shank3 in the nucleus accumbens decreases social motivation in mice without affecting food reward or anxiety.

4 citations

mouseexperimental assay

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