Carolina Leynes

This study identifies impaired luteal resolution and CHK2-regulated inflammation as features of ovarian aging in mice, showing that CHK2 inhibition can reverse these effects.

A combinatorial gene therapy targeting inflammation and chondrocyte health slows OA progression and reduces pain in murine and equine models.

This study identifies validated genetic and tracer tools to map knee-innervating neurons, aiding in understanding joint pain mechanisms.

The paper introduces a standardized, open-source protocol for noninvasive joint injury in mice, resulting in post-traumatic osteoarthritis, and provides tools for reproducibility and analysis.

The paper introduces KneEZ Clear, an aqueous-based tissue clearing method for musculoskeletal tissues that preserves fluorescence and avoids equipment requirements.