Jia Sheng Guan

CrossAffinity predicts protein-protein binding affinity using a sequence-based cross-attention model, outperforming both structure-based and sequence-based methods on multiple test sets.

This paper shows that protein language models can achieve screening performance similar to structure-based methods without requiring 3D protein structures.

This study identifies FDA-approved drugs that may repurpose to treat monkeypox by predicting their binding to viral proteins critical for replication.

Bacteria.guru provides a database for comparative transcriptomics and co-expression networks of bacterial pathogens to aid in understanding gene function and antibiotic resistance.