Synthetic BiologyACS Synthetic BiologyPeer-reviewed
Engineered Bacillus subtilis as oral probiotics to enhance clearance of blood lactate
Mengdi Yang, Noah T. Hutchinson, Ningyuan Ye…·Jiahe Li
This paper engineers Bacillus subtilis spores to deliver lactate oxidase to the gut, reducing blood lactate in mice without disrupting microbiota or organ function.
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