Molecular BiologybioRxivPreprint
Intrinsic RNA targeting constrains the utility of CRISPR-Cas13 systems
Zexu Li, Zihan Li, Xiaolong Cheng…·Fei Teng
The paper evaluates CRISPR-Cas13 systems and finds that they have intrinsic RNA targets in mammalian cells, which can affect lentiviral particle production and limit their utility.
2 citations