Hanze Meng

The paper develops a system for predicting protein-ligand binding sites from Cryo-EM maps and generates drug-like ligands using a combination of PLBP methods and a de novo structure modeling tool.

The paper introduces DeepTracer-2.0, an AI pipeline that automatically models protein-DNA/RNA complexes from cryo-EM maps, improving accuracy and efficiency in macromolecular structure prediction.