Author

Akash Deogharkar

University of MichiganORCID 0009-0003-8980-0484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Abhijit ParoliaiD· 1 shared Ana Azambuja· 1 shared Arul M. ChinnaiyaniD· 1 shared Benita TamraziiD· 1 shared Bryan T. MottiD· 1 shared Carl Johannes KoschmanniD· 1 shared Daniel Richard WahliD· 1 shared Erik R. PetersoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Abhijit ParoliaORCID

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1 paper

Recent·Most cited

Lactate epigenetically shapes tumor cell states in H3K27M diffuse midline gliomas

Joanna Lum, Nicholas Nuechterlein, Shelby Sliger, Sanjana Eyunni, Benita Tamrazi, Stefan Blüml, Wentao Tian, Akash Deogharkar, Stefan R. Sweha, Mateus Mota, Jill M. Bayliss, Erik R. Peterson, Sunjong Ji, Molly Wittwer, Ksheetesha Bhat, , Sriram Venneti

This study shows lactate epigenetically regulates cell states in H3K27M diffuse midline gliomas by modifying histones, and targeting CBP/p300 reduces tumor heterogeneity and improves preclinical outcomes.

bioRxiv · Oct 6, 2026 · PreprintMolecular Biology