Author

Erik R. Peterson

University of MichiganORCID 0000-0002-6579-2948Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carl Johannes KoschmanniD· 3 shared Daniel Richard WahliD· 3 shared Joshua D. ParselsiD· 2 shared Leslie A. ParselsiD· 2 shared Meredith Ann MorganiD· 2 shared Qiang ZhangiD· 2 shared Sriram VennetiiD· 2 shared Theodore Steven LawrenceiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Carl Johannes KoschmannORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Lactate epigenetically shapes tumor cell states in H3K27M diffuse midline gliomas

Joanna Lum, Nicholas Nuechterlein, Shelby Sliger, Sanjana Eyunni, Benita Tamrazi, Stefan Blüml, Wentao Tian, Akash Deogharkar, Stefan R. Sweha, Mateus Mota, Jill M. Bayliss, Erik R. Peterson, Sunjong Ji, Molly Wittwer, Ksheetesha Bhat, , Sriram Venneti

This study shows lactate epigenetically regulates cell states in H3K27M diffuse midline gliomas by modifying histones, and targeting CBP/p300 reduces tumor heterogeneity and improves preclinical outcomes.

bioRxiv · Oct 6, 2026 · PreprintMolecular Biology

Inhibition of H3K27M-enhanced ATM signaling increases radiation efficacy in diffuse midline glioma

Erik R. Peterson, Leslie A. Parsels, Zian Li, Xinyi Zhao, Luke D. Hess, Yupei Guo, Dana Messinger, Joshua D. Parsels, Zhuwen Wang, Tingting Qin, Victoria M. Valvo, Andrea T. Franson, Maria Graciela Castro, Viveka Nand Yadav, Theodore Steven Lawrence, , Meredith Ann Morgan

This study shows that inhibiting ATM signaling with AZD1390 improves radiation efficacy in H3K27M-altered diffuse midline glioma by enhancing DNA damage repair sensitivity.

Molecular Cancer Therapeutics · Jul 14, 2026Peer-reviewedCancer Biology

H3K27M diffuse midline glioma is homologous recombination defective and sensitized to radiotherapy and NK cell-mediated antitumor immunity by PARP inhibition

Yupei Guo, Zian Li, Leslie A. Parsels, Zhuwen Wang, Joshua D. Parsels, Anushka Dalvi, Stephanie The, Nan Hu, Victoria M. Valvo, Robert E. Doherty, Erik R. Peterson, Xinjun Wang, Sujatha Venkataraman, Sameer Agnihotri, Sriram Venneti, , Qiang Zhang

This study shows H3K27M diffuse midline glioma is HRR defective and radiosensitized by PARP inhibitors, with enhanced NK cell-mediated immunity.

Neuro-Oncology · Apr 3, 2025Peer-reviewedCancer Biology