Xiaochuan Fu

This study characterizes lipid droplets in human atherosclerotic plaques, revealing their unique lipid and protein composition, including high levels of inflammatory precursors and cytoskeletal proteins.

This study identifies MNP33, a novel mitochondrial microprotein, and shows it regulates bioenergetics, lipid metabolism, and stress responses by interacting with ANT2 and modulating mitochondrial function.

The paper compares lipid droplet proteomes between endurance athletes and T2DM patients, identifying ATGL and mitochondrial association as factors contributing to higher insulin sensitivity in athletes.