Author

Katherine C. Pan

California Institute of TechnologyORCID 0009-0003-9701-9436Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Assay:long-read sequencing· 1

Frequent Co-Authors

Alexei A. AraviniD· 2 shared Peiwei CheniD· 2 shared Andrew G. ClarkiD· 1 shared Cédric FeschotteiD· 1 shared Eunice H. Park· 1 shared Hamna WaseemiD· 1 shared John McCormick· 1 shared Peiyu XuiD· 1 shared

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2025-2026 · peak 1/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Alexei A. AravinORCID

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2 papers

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedOct 28, 2026

piRNA loss unleashes episodic transposition bursts

Peiwei Chen, Peiyu Xu, Hamna Waseem…·Cédric Feschotte

This study shows that loss of the piRNA pathway in Drosophila leads to episodic and stochastic transposition bursts, not just increased transposition rates.

DOI 10.1073/pnas.2623866123

Drosophilalong-read sequencing

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GeneticsProceedings of the National Academy of SciencesPeer-reviewedJan 7, 2025

Escalation of genome defense capacity enables control of an expanding meiotic driver

Peiwei Chen, Katherine C. Pan, Eunice H. Park…·Alexei A. Aravin

The paper identifies a new defense mechanism in Drosophila that enhances the piRNA pathway to control an expanded meiotic driver by increasing the expression of PIWI-clade nucleases.

11 citationstop 4%

Drosophilaexperimental assay

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