Théo Cavinato

This paper evaluates the feasibility of re-identifying individuals using polygenic predictions and finds that real-world effectiveness is limited due to low priors and poor sensitivity for sensitive genotypes.

The paper detects stabilizing selection on human plasma proteins by integrating genetic and fitness-related evidence across multiple approaches.

The paper estimates genetic assortative mating using haplotype reconstruction in large biobank cohorts, revealing recent trends in mate choice and its genetic impact.

The paper investigates how polygenic scores and copy-number variants interact, finding that assortative mating explains their positive correlation and contributes to genetic risk compounding.

The paper infers parent-of-origin effects in ~265,000 individuals using a novel method, identifying over 30 novel POEs and confirming known associations, supporting the parental conflict hypothesis.

The paper introduces RESHAPE, a method to anonymize reference panels by simulating descendant genomes, enabling genotype imputation while protecting privacy.