Thibault Latrille

Triangulating evidence to detect signatures of stabilizing selection acting on protein levels in humans

The paper detects stabilizing selection on human plasma proteins by integrating genetic and fitness-related evidence across multiple approaches.

Heterogeneous evolution of effective recombination landscapes across percomorph fishes

The paper quantifies recombination landscape divergence across percomorph fish species using PRDI and finds divergence increases with genetic differentiation and divergence time, with variation among species pairs.

DTX3L-PARP9 co-evolve as a single adaptive unit linking ubiquitination and ADP-ribosylation in antiviral immunity

This study shows the DTX3L-PARP9 complex co-evolves as an adaptive unit in antiviral immunity, with adaptive residues enriched at interaction surfaces and catalytic regions.

RegEvol: detection of directional selection in regulatory sequences through phenotypic predictions and phenotype-to-fitness functions

RegEvol detects directional selection in regulatory sequences by linking transcription factor binding predictions to evolutionary models, identifying 5.1% of Drosophila regulatory regions under directional selection.

Phylogram instead of chronogram when assessing the neutral evolution of a trait

The paper argues for using phylograms over chronograms when assessing neutral trait evolution, showing simulations support better model fit with phylograms for neutral traits.

Genetic basis of the evolution of vertical bars in clownfishes

This study investigates the genetic basis of vertical bar evolution in clownfish by analyzing changes in selective pressure on pigmentation-related genes.

Widespread selection relaxation in aquatic mammals

The paper investigates selection relaxation in aquatic mammals and finds it occurs in 20% of genes across both semiaquatic and fully aquatic species.