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Subphase-Labeled Mitotic Dataset for AI-powered Cell Division Analysis

The paper introduces a subphase-labeled mitotic dataset to improve mitosis detection and subtyping, enhancing domain generalization and enabling biological insights into mitotic subphases.

Intrahepatic reporter assay reveals leaky somatic blockade of L1 retrotransposition in mice

The paper demonstrates somatic L1 retrotransposition in adult mouse liver using an intrahepatic reporter assay and identifies distinct regulatory mechanisms in tumor versus normal cells.

Comprehensive Bulk and Single-Cell RNA Sequencing Uncovers Senescence-Associated Biomarkers in Therapeutic Mesenchymal Stem Cells

The paper uses bulk and single-cell RNA sequencing to identify senescence-associated biomarkers in canine mesenchymal stem cells across passages.

The Cause of Most Common Antler Abnormality is Not a Fracture But an Osteomyelitis Like Disease the Pedunculitis Chronica Deformans

The study identifies an osteomyelitis-like disease, Pedunculitis Chronica Deformans, as the cause of common antler abnormalities in fallow deer, linked to mycotoxin exposure from climate change.

Show me your neighbour and I tell what you are: fisheye transformation for deep learning-based single-cell phenotyping

The paper introduces a fisheye transformation for single-cell phenotyping, improving accuracy by weighting nearby cells more heavily than distant ones, and validates it on microscopy and wildlife datasets.

Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria

The paper develops an engineered bacterium-based RNA interference therapy that reduces inflammation in an IBD model by targeting TNF-alpha.

Show me your neighbours, and I’ll tell you what you are – cellular microenvironment matters

The paper shows that incorporating microenvironmental features improves machine learning-based single-cell phenotyping in imaging data.