BiochemistryAdvanced SciencePeer-reviewed
Decoding the Mechanism of Action of a Parasite TGFβAntagonist Inspires the Creation of Cell-type-specific TGFβ Modulators
Maarten van Dinther, Tristin A. Schwartze, Jiying Zhang…·Peter ten Dijke
This paper identifies co-receptors for a parasite TGFβ antagonist, uses structural data to design cell-type-specific TGFβ modulators, and demonstrates their selective antagonistic effects.
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