Author

Jordan E. Mancuso

insitro, inc. (United States)ORCID 0009-0004-1681-9405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

Devon A. StorkiD· 2 shared Edward SukartoiD· 2 shared Erika Alden DeBenedictisiD· 2 shared Fatima R Martin· 2 shared Harley Greene· 2 shared Jonathan Liu· 2 shared Keren IsaeviD· 2 shared Max G SchubertiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Devon A. StorkORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 10, 2026

Defined Mars Media (DMM), a chemically defined simulant of the soluble macro- and micro- nutrients in Mars regolith for use in biological research

Harley Greene, Una Nattermann, Devon A. Stork…·Erika Alden DeBenedictis

This paper introduces DMM, a defined Mars media simulating Martian regolith nutrients and stressors, and demonstrates microbial growth using it.

DOI 10.64898/2026.04.24.719001

experimental assay

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MicrobiologybioRxivPreprintMay 4, 2026

BioBloom, a method for barcoded saturation mutagenesis of an entire bacterial genome

Max G Schubert, Edward Sukarto, Fatima R Martin…·Erika Alden DeBenedictis

BioBloom enables whole-genome barcoded saturation mutagenesis in E. coli, identifying beneficial mutations under salt and antibiotic selection with high coverage and efficiency.

1 citation

E. coliwhole-genome sequencing

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GenomicsNature CommunicationsPeer-reviewedDec 16, 2025

A Pooled Cell Painting CRISPR Screening Platform Enables de novo Inference of Gene Function by Self-supervised Deep Learning

Srinivasan Sivanandan, Bobby Leitmann, Eric Lubeck…·Ci Chu

This paper introduces a pooled CRISPR screening platform combined with self-supervised deep learning to infer gene function from morphological phenotypes without target-specific biomarkers.

35 citationstop 1%

humanCRISPR screen

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