Erika Alden DeBenedictis

This study demonstrates the production of PHA bioplastic from simulated 100% Martian resources using engineered microbes.

This paper introduces DMM, a defined Mars media simulating Martian regolith nutrients and stressors, and demonstrates microbial growth using it.

The paper introduces GROQ-seq, a high-throughput platform for linking protein function to sequencing data, and presents pilot datasets for transcription factors, polymerases, and proteases.

This study demonstrates that GROQ-seq provides reproducible, scalable measurements of protein function across different facilities.

BioBloom enables whole-genome barcoded saturation mutagenesis in E. coli, identifying beneficial mutations under salt and antibiotic selection with high coverage and efficiency.

This paper evolves a halogenase enzyme to improve solubility and activity, enabling higher yields of halogenated compounds for sustainable bioproduction.

The paper introduces a protein engineering competition to benchmark computational models for protein design and characterization, with results from a pilot tournament involving seven teams.

The paper introduces SubtiToolKit, a cloning toolkit for Bacillus subtilis and Gram-positive bacteria, enabling efficient DNA construct design for various genetic applications.

The paper identifies fluoride contamination from glass NMR tubes and proposes a simple solution to mitigate it in biomolecular applications.

The paper introduces a method combining exact-match search with functional variant prediction to automate DNA synthesis screening for controlled genes.

This study examines how E. coli's genetic code tolerates tRNA mutations that increase codon size, finding that while many tRNAs can be converted to quadruplet tRNAs, only nine aminoacyl tRNA synthetases tolerate quadruplet anticodons, limiting the chemical alphabet of a synthetic quadruplet code.