Anti-Parasitics with a Triple Threat: Targeting Parasite Enzymes, the Proton Motive Force, and Host Cell-Mediated Killing
Akanksha M. Pandey, Satish R. Malwal, Mariana Valladares-Delgado, Liesangerli Labrador-Fagúndez, Bruno G. Stella, Luis José Díaz-Pérez, André Rey-Cibati, Davinder Singh, Μarianna Stampolaki, Sangjin Hong, Robert B. Gennis, Antonios Kolocouris, Gustavo Benaím, Eric Oldfield
This paper evaluates the anti-parasitic effects of SQ109 and MeSQ109 against Leishmania mexicana and investigates their mechanism of action, including mitochondrial and acidocalcisome targeting.
ACS Infectious Diseases · May 6, 2025Peer-reviewedMicrobiology