Author

Μarianna Stampolaki

Max Planck SocietyORCID 0000-0002-0144-4792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Akanksha M. PandeyiD· 1 shared André Rey-CibatiiD· 1 shared Andrei LeonoviD· 1 shared Antonios KolocourisiD· 1 shared Armin GieseiD· 1 shared Benedikt FriegiD· 1 shared Bert L. de GrootiD· 1 shared Bruno G. StellaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Akanksha M. PandeyORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The clinical drug candidate anle138b binds predominantly to the central cavity in lipidic Aβ fibrils and modulates fibril formation.

Mookyoung Han, Benedikt Frieg, Dirk Matthes, Andrei Leonov, Sergey Ryazanov, Karin Giller, Evgeny Nimerovsky, Μarianna Stampolaki, Kai Xue, Kerstin Overkamp, Christian Dienemann, Dietmar Riedel, Armin Giese, Stefan Becker, Bert L. de Groot, , Christian Griesinger

This paper shows that anle138b binds to a cavity in lipidic Aβ fibrils and reduces fibril formation by 75%, suggesting a potential therapeutic mechanism for Alzheimer's disease.

bioRxiv · May 30, 2025 · PreprintBiochemistry

Anti-Parasitics with a Triple Threat: Targeting Parasite Enzymes, the Proton Motive Force, and Host Cell-Mediated Killing

Akanksha M. Pandey, Satish R. Malwal, Mariana Valladares-Delgado, Liesangerli Labrador-Fagúndez, Bruno G. Stella, Luis José Díaz-Pérez, André Rey-Cibati, Davinder Singh, Μarianna Stampolaki, Sangjin Hong, Robert B. Gennis, Antonios Kolocouris, Gustavo Benaím, Eric Oldfield

This paper evaluates the anti-parasitic effects of SQ109 and MeSQ109 against Leishmania mexicana and investigates their mechanism of action, including mitochondrial and acidocalcisome targeting.

ACS Infectious Diseases · May 6, 2025Peer-reviewedMicrobiology