BiochemistrybioRxivPreprint
Structure, dynamics, and processing of 8oxoG:A in the nucleosome
Abigayle F. Vito, Justin A. Ling, Julia C. Ferrara…·Bret Freudenthal
This study determines the structure and dynamics of 8oxoG:C and 8oxoG:A base pairs in the nucleosome and characterizes MUTYH activity, revealing that 8oxoG:A is less processable by MUTYH.
DOI 10.1101/2025.09.02.673820