Author

Kuan Hu

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0009-0004-2549-629XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Siqi ZhangiD· 3 shared Hongyi Huang· 2 shared Mengjie Yang· 2 shared Rui WangiD· 2 shared Tongtong ZhangiD· 2 shared Xuekai Song· 2 shared Can LiuiD· 1 shared Dengfu Wu· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersBiophysics

Siqi ZhangORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 21, 2026

Mechano-Piezoelectric F-Peptide Hydrogels Enable In Situ Stem Cell and Immune Niche Modulation for Cartilage Regeneration

Xuekai Song, Zhaowen Xu, Siqi Zhang…·Kuan Hu

This paper develops a mechano-piezoelectric peptide hydrogel that modulates stem cell and immune niches to reverse osteoarthritis by combining piezoelectric cues with 4-OI loading.

DOI 10.64898/2026.08.18.745416

humanexperimental assay

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Cancer BiologybioRxivPreprintJan 12, 2026

Development of Integrin α5β1-targeted PET/NIR imaging probes for glioblastoma intraoperative navigation and intracavity targeted radionuclide therapy

Siqi Zhang, Jieting Shen, Yiming Li…·Kuan Hu

This paper develops integrin α5β1-targeted PET/NIR imaging probes for glioblastoma surgery and radionuclide therapy, showing improved tumor resection and reduced recurrence.

DOI 10.64898/2026.01.09.698741

mouseimaging

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Molecular BiologybioRxivPreprintJan 8, 2026

Ac-FAPI-04 Promotes Anti-tumor Immunity via IL-27 Activation and Tnfaip3 Inhibition

Shuo Jiang, Siqi Zhang, Tongtong Zhang…·Kuan Hu

This study investigates how [225Ac]Ac-FAPI-04 remodels the tumor microenvironment by activating IL-27 and inhibiting Tnfaip3, enhancing CTL activity and anti-tumor immunity.

DOI 10.64898/2026.01.07.698054

mousebulk RNA-seq

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