Author

Lewis Frame

University of YorkORCID 0009-0004-2949-3520Unclaimed ORCID profile · follow to get notified of new preprints

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Lewis Frame3 papers · University of York

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Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

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Agnes NoyiD· 1 shared Allison H. SquiresiD· 1 shared Antoinette Alevropoulos-Borrill· 1 shared Ayesha EjaziD· 1 shared Benjamin Ambrose· 1 shared Jamieson A. L. HowardiD· 1 shared Lara Dresser· 1 shared Mahmoud A. S. AbdelhamidiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Agnes NoyORCID

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1 paper

Recent·Most cited

BiophysicsNucleic Acids ResearchPeer-reviewedDec 18, 2025

The transitional kinetics between open and closed Rep structures can be tuned by salt via two intermediate states

Jamieson A. L. Howard, Benjamin Ambrose, Mahmoud A. S. Abdelhamid…·Mark C. Leake

This study investigates the conformational transitions of Rep helicase using single-molecule techniques, revealing two intermediate states influenced by salt concentration.

1 citation

bacteria (other)fluorescence / live-cell microscopy

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