Author

Xiayan Qin

Changping LaboratoryORCID 0009-0004-2977-3071Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Baihui TianiD· 1 shared Di WangiD· 1 shared Hongzhun WangiD· 1 shared Jie LiniD· 1 shared Liangyue GuoiD· 1 shared Mingchen CheniD· 1 shared Qilin YuiD· 1 shared Xikun HuangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Baihui TianORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

High-Affinity Protein Binder Design via Flow Matching and In Silico Maturation

Qilin Yu, Liangyue Guo, Xiayan Qin, Xikun Huang, Baihui Tian, Hongzhun Wang, Yu Liu, Yunzhi Lang, Di Wang, Zhongkai Shen, Jie Lin, Mingchen Chen

This paper designs high-affinity protein binders using a computational framework combining flow matching and in silico maturation, achieving picomolar and nanomolar affinities without experimental screening.

bioRxiv · Jan 23, 2026 · PreprintBiochemistry