Cell BiologyBlood AdvancesPeer-reviewed
Selective degradation of platelet BTK by PROTAC NX-5948 provides antithrombotic benefits without affecting haemostasis
Carl May, Justin S. Trory, Connor E. Webb…·Ingeborg Hers
This paper shows that NX-5948, a BTK degrader, reduces thrombosis without affecting haemostasis by selectively degrading platelet BTK.
DOI 10.1182/bloodadvances.2026019769