Author

Johannes Andreas Eble

University of MünsterORCID 0000-0001-9156-2137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alastair W. PooleiD· 1 shared Alfredo Cabrera‐OreficeiD· 1 shared Andreas VilcinskasiD· 1 shared Änne SchmitziD· 1 shared Benno KreuelsiD· 1 shared Björn HilliD· 1 shared Carl MayiD· 1 shared Connor E. WebbiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperCell Biology

Alastair W. PooleORCID

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4 papers

Recent·Most cited

Selective degradation of platelet BTK by PROTAC NX-5948 provides antithrombotic benefits without affecting haemostasis

Carl May, Justin S. Trory, Connor E. Webb, Hetty S. Walker, Yong Li, Jonathan Alan Furniss, Johannes A. Eble, Alastair W. Poole, Jordan Vautrinot, Jay Tromans, Ingeborg Hers

This paper shows that NX-5948, a BTK degrader, reduces thrombosis without affecting haemostasis by selectively degrading platelet BTK.

Blood Advances · Jun 30, 2026Peer-reviewedCell Biology

A critical role for VE-cadherin in regulating actin dynamics during endothelial maturation and non-inflammatory activation via a tension-sensitive intermediate state

Jonas Franz, Maria Odenthal-Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Johannes Andreas Eble, Erez Raz, Milos Galic, Hans‐Joachim Schnittler

The paper identifies a tension-sensitive intermediate state in endothelial cells during non-inflammatory activation, which regulates actin dynamics and barrier function through VE-cadherin and MLC-dephosphorylation.

bioRxiv · Aug 5, 2025 · PreprintCell Biology

Low extent of sex-based venom variation in Earth's most widespread viper, the common adder (Vipera berus)

Lennart Schulte, Miguel Engelhardt, Johanna Eichberg, Alfredo Cabrera‐Orefice, Harry Wölfel, Maik Damm, Ignazio Avella, Benno Kreuels, Kornelia Hardes, Johannes Andreas Eble, Andreas Vilcinskas, Tim Lüddecke

The paper investigates sex-based venom variation in the common adder, finding minimal differences in venom profiles and bioactivity between sexes.

bioRxiv · Mar 27, 2025 · PreprintBiochemistry

Rapid catecholamine trafficking regulates neutrophil functions and neutrophil-platelet interactions

Jennifer M. Mohr, Änne Schmitz, Meshkat Dinarvand, Sangeetha Shankar, Björn Hill, Franziska Wulfert, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Andreas Eble, Luise Erpenbeck, Sebastian Kruss

The paper shows human neutrophils take up and release catecholamines like dopamine and epinephrine, similar to neurons, and identifies a neutrophil-platelet feedback loop involved in inflammation and coagulation.

bioRxiv · Jan 27, 2025 · PreprintImmunology