Author
University of BristolORCID 0000-0002-0868-297XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Iara Aimê Cardoso, Sophie Hall, Thomas Crasset…·Christiane Schaffitzel
This study characterizes recombinant disintegrins from Echis species, showing distinct inhibitory effects on platelet aggregation and endothelial cell migration.
Sophie Hall, B. O. Rand, Iara Aimê Cardoso…·Christiane Schaffitzel
This study investigates the roles of disintegrin-like and cysteine-rich domains in substrate recognition and catalytic activity of PIII snake venom metalloproteinases using recombinant variants and functional assays.
Carl May, Justin S. Trory, Connor E. Webb…·Ingeborg Hers
This paper shows that NX-5948, a BTK degrader, reduces thrombosis without affecting haemostasis by selectively degrading platelet BTK.
Sophie Hall, Iara Aimê Cardoso, Mark C. Wilkinson…·Christiane Schaffitzel
The paper develops a method to produce and activate purified snake venom metalloproteinases (SVMPs) using recombinant zymogens, enabling detailed biochemical and functional analysis.