Author

Yasuhiro Horibata

Dokkyo Medical UniversityORCID 0009-0004-3384-4354Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Akane HubbardiD· 1 shared Akimitsu KonishiiD· 1 shared Ashleigh M. RaczkowskiiD· 1 shared Betsy White· 1 shared Frank E. KwarcinskiiD· 1 shared Gregory G. TalliD· 1 shared Hiroyuki Sugimoto· 1 shared Hiroyuki SugimotoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Akane HubbardORCID

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2 papers

Recent·Most cited

Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy

Yasuhiro Horibata, Tomoki Sato, Masahide Ohyama, Sae Yuyama, Masahiko Itoh, Shinji Miura, Akimitsu Konishi, Hiroyuki Sugimoto

This study shows that STARD7 loss disrupts mitochondrial phospholipid homeostasis, leading to impaired function and myopathy in skeletal muscle.

The FASEB Journal · Apr 16, 2026Peer-reviewedBiochemistry

Structural basis for catalysis and selectivity of phospholipid synthesis by eukaryotic choline-phosphotransferase

Jacquelyn R. Roberts, Yasuhiro Horibata, Frank E. Kwarcinski, Vinson Lam, Ashleigh M. Raczkowski, Akane Hubbard, Betsy White, Hiroyuki Sugimoto, Gregory G. Tall, Melanie D. Ohi, Shoji Maeda

The paper presents the structure of yeast CPT1 in multiple substrate-bound states to elucidate the mechanism of phospholipid synthesis and selectivity.

Nature Communications · Jan 2, 2025Peer-reviewedBiochemistry