BiochemistryNature CommunicationsPeer-reviewed
β-arrestin recruitment facilitates a direct association with G proteins
Claudia Y. Lee, Jeffrey S. Smith, Taylor Kohlmann…·Sudarshan Rajagopal
This study shows that G proteins and β-arrestins can directly interact, with Gi family members differing in their association with β-arrestin, and this selectivity is located in the alpha helical domain of Gi.
DOI 10.1038/s41467-026-74944-7