Author

Sophia N. Lee

Yale UniversityORCID 0009-0004-3517-1990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Erin C. BandaiD· 1 shared Jason M. SheltzeriD· 1 shared Karan SinghiD· 1 shared Lu QiaoiD· 1 shared Ryan A. HagensoniD· 1 shared Sarah L. ThompsoniD· 1 shared Stefan F. PinteriD· 1 shared Teresa DavoliiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperDevelopmental Biology

Erin C. BandaORCID

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1 paper

Recent·Most cited

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

Sophia N. Lee, Erin C. Banda, Lu Qiao, Sarah L. Thompson, Karan Singh, Ryan A. Hagenson, Teresa Davoli, Stefan F. Pinter, Jason M. Sheltzer

This study corrects a complex Chromosome 8 rearrangement in vitro, identifies differentially expressed genes, and shows partial rescue of neural differentiation defects.

Genome Research · Mar 1, 2026Peer-reviewedDevelopmental Biology