Author

Aarthi Nivasini Mahesh

National University of SingaporeORCID 0009-0004-4072-7543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ahmed M. MamdouhiD· 1 shared Alexandre PuissantiD· 1 shared Brandon Douglas BrowniD· 1 shared Camille LobryiD· 1 shared Cheryl Gek Teng Chan· 1 shared Chuqi WangiD· 1 shared Edward AyoubiD· 1 shared Elyse A. OlesinskiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ahmed M. MamdouhORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

BIRC5 dependency defines a targetable vulnerability in TP53 mutant acute myeloid leukemia

Ahmed M. Mamdouh, Fang Qi Lim, Yang Mi, Elyse A. Olesinski, Shaista Shabbir Jasdanwala, Xiao Xian Lin, Edward Ayoub, Jordan Yong Ming Tan, Karanpreet Singh Bhatia, Yichen Wang, Shradha Garnaik, Kunal Tomar, Valeriia Sapozhnikova, Cheryl Gek Teng Chan, Chuqi Wang, , Shruti Bhatt

This study identifies BIRC5 as a targetable vulnerability in TP53 mutant AML, showing that survivin/IAP inhibitors can overcome therapy resistance.

bioRxiv · May 17, 2025 · PreprintCancer Biology