Author

Margaret Y Sui

California Institute of TechnologyORCID 0009-0004-4129-0902Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:trajectory inference· 1

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Carlos LoisiD· 1 shared Chen GuiiD· 1 shared Duncan M. ChadlyiD· 1 shared Kirsten L. Frieda· 1 shared Leslie KlockiD· 1 shared Long CaiiD· 1 shared Martin TraniD· 1 shared Michael B. ElowitziD· 1 shared

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1 shared paperSynthetic Biology

Carlos LoisORCID

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Synthetic BiologybioRxivPreprintJan 3, 2024

Reconstructing cell histories in space with image-readable base editor recording

Duncan M. Chadly, Kirsten L. Frieda, Chen Gui…·Michael B. Elowitz

This paper introduces baseMEMOIR, a method that reconstructs high-resolution cell lineage trees and spatial dynamics using base editing and imaging, achieving 792 bits of memory in embryonic stem cells.

25 citations

mouseDNA methylation

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