Saahithi Mallapragada

The paper combines two spatial transcriptomic chemistries to improve both sensitivity and coverage in a single tissue section, showing high concordance and enabling more comprehensive analysis.

This paper creates a spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity using 1.2 million cells from 17 human infant lungs.

The paper identifies loss of semaphorin signaling and reduced FOXF1 expression in BPD and BPD+PH using single-cell RNA sequencing and validates findings in a murine model.