Author

Aiko M. Cirone

ORCID 0009-0004-4350-2913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adam L. SobeliD· 1 shared Dominic A. HaasiD· 1 shared Eduard AnsaldoiD· 1 shared Elizabeth MurguiaiD· 1 shared Gabrielle LeBlanciD· 1 shared Jonathan MelamediD· 1 shared Michael G. ConstantinidesiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Adam L. SobelORCID

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1 paper

Recent·Most cited

Antibiotic use in early life subsequently impairs MAIT cell-mediated immunity

Gabrielle LeBlanc, Adam L. Sobel, Jonathan Melamed, Dominic A. Haas, Eduard Ansaldo, Aiko M. Cirone, Elizabeth Murguia, Michael G. Constantinides

This study shows that early-life antibiotic use reduces MAIT cell abundance, impairing immunity to pneumonia, but this effect can be reversed by reintroducing riboflavin-synthesizing commensals.

The Journal of Experimental Medicine · Nov 19, 2025Peer-reviewedImmunology