Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia
Michael A. Swanson, Hua Jiang, Nicolas Busquet, Jessica Carlsen, Connie Brindley, Tim A. Benke, Roxanne A. Van Hove, Marisa W. Friederich, Kenneth N. Maclean, Michael H. Mesches, Johan L.K. Van Hove
This paper describes a new mouse model of nonketotic hyperglycinemia with postnatal abnormalities in glycine levels, neural tube defects, body weight, electroencephalographic recordings, and activity, useful for evaluating new therapies.
Journal of Inherited Metabolic Disease · Jun 5, 2024Peer-reviewedAnimal Behavior & Cognition