Author

Michael H. Mesches

University of Colorado AnschutzORCID 0000-0002-4182-7413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Assay:proteomics· 1

Frequent Co-Authors

Nicolas BusquetiD· 2 shared Anushree ChatterjeeiD· 1 shared Connie BrindleyiD· 1 shared Elizabeth J. KovacsiD· 1 shared Hua JiangiD· 1 shared Jessica CarlseniD· 1 shared Johan L.K. Van HoveiD· 1 shared Julie A. MorenoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

Nicolas BusquetORCID

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2 papers

Recent·Most cited

Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia

Michael A. Swanson, Hua Jiang, Nicolas Busquet, Jessica Carlsen, Connie Brindley, Tim A. Benke, Roxanne A. Van Hove, Marisa W. Friederich, Kenneth N. Maclean, Michael H. Mesches, Johan L.K. Van Hove

This paper describes a new mouse model of nonketotic hyperglycinemia with postnatal abnormalities in glycine levels, neural tube defects, body weight, electroencephalographic recordings, and activity, useful for evaluating new therapies.

Journal of Inherited Metabolic Disease · Jun 5, 2024Peer-reviewedAnimal Behavior & Cognition

NF-kB/NLRP3 Translational Inhibition by Nanoligomer Therapy Mitigates Ethanol and Advanced Age-Related Neuroinflammation

Paige E. Anton, Prashant Nagpal, Julie A. Moreno, Matthew A. Burchill, Anushree Chatterjee, Nicolas Busquet, Michael H. Mesches, Elizabeth J. Kovacs, Rebecca L. McCullough

This study shows that binge ethanol increases NLRP3+ microglia in aged mice, and that Nanoligomer therapy reduces ethanol-induced neuroinflammation and tau hyperphosphorylation.

bioRxiv · Feb 26, 2024 · PreprintNeuroscience