Takuto Yamamoto

This study compares the lethality-inducing potential of Bax, Casp3, and Casp9 in mouse early embryos and finds Bax most effective in causing embryo death.

This study identifies Pcgf5, a MERVL-regulated chimeric transcript, as critical for zygotic genome activation and noncanonical imprinting in mouse embryos.

The paper shows that NSUN5 is critical for mouse preimplantation development by regulating Hippo signaling, cell proliferation, and lineage segregation.

This study shows that Myc is essential for zygotic genome activation (ZGA) and preimplantation development in mouse embryos.

This study introduces an electroporation method to suppress maternal effect genes in mouse oocytes without removing cumulus cells, showing efficient maternal mRNA suppression and revealing H3.3's role in post-fertilization development.