Characterisation of the RNA-Binding Properties of the MRSA β-lactam resistance enzyme PBP2a
Niki Christopoulou, Ngo Hong Duong, Pedro Arêde Rei, Gabriel Torrens, Matthieu Blandenet, Felipe Cava, Sander Granneman
This study identifies PBP2a as an RNA-binding protein in MRSA, showing it interacts with hundreds of transcripts and its RNA-binding activity is crucial for oxacillin resistance.
bioRxiv · Jul 7, 2026 · PreprintBiochemistry